Preferred Label : WT1-Sensitized Allogeneic T-Lymphocytes;
NCIt definition : A population of allogeneic T-cells sensitized with Wilms tumor 1 (WT1) antigen with
potential immunostimulatory and antineoplastic activities. Upon administration, WT1-sensitized
T cells may bind to and lyse WT1-expressing tumor cells. WT1 antigen, a zinc finger
DNA-binding protein acting as a transcriptional activator or repressor depending on
the cellular or chromosomal context, is overexpressed in leukemic cells and in a vast
number of nonhematological solid tumors.;
Origin ID : C74091;
UMLS CUI : C2349140;
Semantic type(s)
- Cell [UMLS semantic type]
- concept_is_in_subset
- has_target
