" /> Rexinoid NRX 194204 - CISMeF





Preferred Label : Rexinoid NRX 194204;

NCIt related terms : VTP-194204;

NCIt definition : An orally bioavailable synthetic retinoid X receptor (RXR) agonist with potential antineoplastic and anti-inflammatory activities. Rexinoid NRX 194204 selectively binds to and activates RXRs. Because RXRs can form heterodimers with several nuclear receptors (NRs), RXR activation by this agent may result in a broad range of gene expression depending on the effector DNA response elements activated. Rexinoid NRX 194204 may inhibit the tumor-necrosis factor (TNF)-mediated release of nitric oxide (NO) and interleukin 6 (IL6) and may inhibit tumor cell proliferation. This agent appears to be less toxic than RAR-selective ligands.;

UNII : 877M97Z38Y;

CAS number : 260262-39-3;

Molecule name : NRX194204; AGN194204;

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31/05/2025


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