" /> MET Tyrosine Kinase Inhibitor SGX523 - CISMeF





Preferred Label : MET Tyrosine Kinase Inhibitor SGX523;

NCIt related terms : SGX-523;

NCIt definition : An orally bioavailable small molecule, c-Met inhibitor with potential antineoplastic activity. MET receptor tyrosine kinase inhibitor SGX523 specifically binds to c-Met protein, or hepatocyte growth factor receptor (HGFR), preventing binding of hepatocyte growth factor (HGF) and disrupting the MET signaling pathway; this agent may induce cell death in tumor cells expressing c-Met. c-Met, a receptor tyrosine kinase overexpressed or mutated in many tumor cell types, plays an important role in tumor cell proliferation, survival, invasion, and metastasis, and in tumor angiogenesis.;

UNII : WH8SQN09KJ;

CAS number : 1022150-57-7;

Molecule name : SGX523;

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29/07/2025


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