Liposomal MnSOD Plasmid

Preferred Label : Liposomal MnSOD Plasmid;

NCIt synonyms : MnSOD Plasmid Liposomes; MnSOD-PL;

NCIt definition : A plasmid DNA encoding human manganese superoxide dismutase (MnSOD) and liposomally encapsulated with potential chemoprotective activity. When administered orally and localizing in the esophagus, MnSOD-plasmid liposomes express MnSOD, which scavenges reactive oxygen species (ROS); MnSOD scavenging of ROS may result in a reduction in ROS-mediated lipid peroxidation, apoptosis, and micro-ulceration in the epithelial lining of the esophagus.;

NCI Metathesaurus CUI : CL383936;

Details

Origin ID

C74054;

UMLS CUI

C2346683;

Semantic type(s)
- Biologically Active Substance [UMLS semantic type]
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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