Fluciclatide F 18

Preferred Label : Fluciclatide F 18;

NCIt synonyms : 18F-AH111585; Fluorine F 18-RGD AH111585; Fluorine F 18 RGD-based Integrin Peptide-polymer AH111585;

NCIt related terms : FLUCICLATIDE F-18;

NCIt definition : A radiopharmaceutical compound of a small synthetic cyclic peptide containing an RGD-sequence (Arg-Gly-Asp) labeled with the positron-emitting isotope fluorine F 18 that may be used to selectively image tumor cells and tumor vasculature by PET imaging. The RGD motif of fluciclatide F 18 selectively binds to the alphaVbeta3 integrin receptor, commonly upregulated on the surfaces of tumor cells and endothelial cells of tumor vasculature. This agent may be of use in visualizing and quantifying the development of tumor vascularity in response to antiangiogenic agents.;

UNII : HH9UGU71P8;

InChIKey : VXFFXZSNVKXXIB-JZNCAEBOSA-N;

CAS number : 879894-01-6;

Molecule name : [18F]AH111585;

Details

Origin ID

C74031;

UMLS CUI

C2987729;

Automatic exact mappings (from CISMeF team)
- (18F)fluciclatide [MeSH concept]
- AH 111585 [MeSH Supplementary Concept]
- Fluciclatide (18-F) (substance) [SNOMED CT concept]
- Product containing fluciclatide (18-F) (medicinal product) [SNOMED CT concept]
Currated CISMeF NLP mapping
- 18F-AH111585 [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Indicator, Reagent, or Diagnostic Aid [UMLS semantic type]
UMLS correspondences (same concept)
- Fluciclatide (18-F) (substance) [SNOMED CT concept]
- Product containing fluciclatide (18-F) (medicinal product) [SNOMED CT concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_target
- Integrin AlphaV/Beta3 [NCIt concept]

Keyword's position in hierarchy(ies) :

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