Apricoxib - CISMeF

Preferred Label : Apricoxib;

NCIt synonyms : COX-2 Inhibitor TG01;

NCIt definition : An orally bioavailable nonsteroidal anti-inflammatory agent (NSAID) with potential antiangiogenic and antineoplastic activities. Apricoxib binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), thereby inhibiting the conversion of arachidonic acid into prostaglandins. Apricoxib-mediated inhibition of COX-2 may induce tumor cell apoptosis and inhibit tumor cell proliferation and tumor angiogenesis. COX-related metabolic pathways may represent crucial regulators of cellular proliferation and angiogenesis.;

UNII : 5X5HB3VZ3Z;

InChIKey : JTMITOKKUMVWRT-UHFFFAOYSA-N;

CAS number : 197904-84-0; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 197904-84-0 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : R-109339; CS-706; TP2001; TG01;

Chemical formula : C19H20N2O3S;

Details

Origin ID

C74021;

UMLS CUI

C1737955;

Currated CISMeF NLP mapping
- apricoxib [MeSH Supplementary Concept]
- apricoxib [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- apricoxib [MeSH concept]
- apricoxib [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Prostaglandin G/H Synthase 2 [NCIt concept]

Keyword's position in hierarchy(ies) :

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