Hairy Cell Leukemia

Preferred Label : Hairy Cell Leukemia;

NCIt synonyms : Leukemic Reticuloendotheliosis; HCL;

NCIt definition : A neoplasm of small B-lymphocytes with hairy projections in bone marrow, spleen, and peripheral blood. Most patients present with splenomegaly and pancytopenia. (WHO, 2001);

Alternative definition : NCI-GLOSS: A rare type of leukemia in which abnormal B-lymphocytes (a type of white blood cell) are present in the bone marrow, spleen, and peripheral blood. When viewed under a microscope, these cells appear to be covered with tiny hair-like projections.;

Neoplastic status : Malignant;

ICD-O code : 9940/3;

Codes from synonyms : 10019053; CDR0000045159;

Details

Origin ID

C7402;

UMLS CUI

C0023443;

Currated CISMeF NLP mapping
- Classic hairy cell leukemia [ORDO Disease]
- HAIRY CELL LEUKAEMIA [WHO-ART Preferred Term]
- Hairy cell leukaemia [ICD-11 Extension code]
- Hairy cell leukaemia [MedDRA Preferred Term]
- Hairy cell leukemia [PASCAL descriptor]
- Hairy cell leukemia [ICD-10 Sub-category]
- Hairy cell leukemia [ICD-9 code]
- Hairy cell leukemia [ICD-O code]
- Hairy cell leukemia [MedDRA LLT]
- Hairy cell leukemia (disorder) [SNOMED CT concept]
- Hairy cell leukemia (morphologic abnormality) [SNOMED CT concept]
- Hairy-cell leukaemia [ICD-11 Subcategory]
- Hairy-cell leukaemia [ICD-10 Sub-category (who)]
- Leukaemic reticuloendotheliosis [MedDRA LLT]
- Leukemic reticuloendotheliosis [MedDRA LLT]
- hairy cell leukemia [DO Concept]
- hairy cell leukemia [Disease (Nov.)]
- hairy cell leukemia [SNOMED Notion]
- leukemia, hairy cell [MeSH Descriptor]
- leukemia, hairy cell [MeSH concept]
DO Cross reference
- hairy cell leukemia [DO Concept]
Disease excludes abnormal cell
- Leukemic Plasma Cell [NCIt concept]
- Neoplastic T-Lymphocyte and Neoplastic Natural Killer Cell [NCIt concept]
Disease excludes normal cell origin
- Myeloid Cell [NCIt concept]
- Precursor B-Lymphoblast [NCIt concept]
Has associated anatomic sites
- Hematopoietic and Lymphatic System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Classic hairy cell leukemia [ORDO Disease]
- HAIRY CELL LEUKAEMIA [WHO-ART Preferred Term]
- Hairy cell leukaemia [MedDRA Preferred Term]
- Hairy cell leukemia [MedDRA LLT]
- Hairy cell leukemia [ICD-O code]
- Hairy cell leukemia [ICD-10 Sub-category]
- Hairy cell leukemia [PASCAL descriptor]
- Hairy cell leukemia (disorder) [SNOMED CT concept]
- Hairy cell leukemia (morphologic abnormality) [SNOMED CT concept]
- Hairy-cell leukaemia [ICD-11 Subcategory]
- Hairy-cell leukaemia [ICD-10 Sub-category (who)]
- Leukaemic reticuloendotheliosis [MedDRA LLT]
- Leukemic reticuloendotheliosis [MedDRA LLT]
- Leukemic reticuloendotheliosis [ICD-9 code]
- hairy cell leukemia [DO Concept]
- hairy cell leukemia [Disease (Nov.)]
- hairy cell leukemia [SNOMED Notion]
- leukemia, hairy cell [MeSH concept]
- leukemia, hairy cell [MeSH Descriptor]
concept_is_in_subset
- CPTAC Codelists Terminology [NCIt concept]
- CPTAC Neoplasms Codelist [NCIt concept]
- CPTAC Terminology [NCIt concept]
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- Cellosaurus Disease Terminology [NCIt concept]
- Cellosaurus Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology Terminology [NCIt concept]
- Mapped ICDO3.1 Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology Terminology [NCIt concept]
- Mapped ICDO3.2 Terminology [NCIt concept]
- NCI CTEP SDC Chronic Lymphoid Leukemia Sub-Category Terminology [NCIt concept]
- NCI CTEP Simplified Disease Classification Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
disease_excludes_finding
- Acute Clinical Course [NCIt concept]
- Benign Cellular Infiltrate [NCIt concept]
- Solid Growth Pattern [NCIt concept]
disease_has_abnormal_cell
- Abnormal Lymphocyte [NCIt concept]
- Hairy Cell [NCIt concept]
- Leukemic Cell [NCIt concept]
- Leukemic Lymphocyte [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic B-Lymphocyte [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Lymphocyte [NCIt concept]
disease_has_finding
- BRAF V600E Mutation Present [NCIt concept]
- Fried-Egg Appearance of the Bone Marrow [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Reticulin Fibrosis of the Bone Marrow [NCIt concept]
- Splenomegaly [NCIt concept]
- Tartrate Resistant Acid Phosphatase Positive Cells Present [NCIt concept]
disease_has_molecular_abnormality
- Clonal Immunoglobulin Gene Rearrangement [NCIt concept]
- Clonal Immunoglobulin Heavy Chain Gene Rearrangement [NCIt concept]
- Clonal Immunoglobulin Kappa Light Chain Gene Rearrangement [NCIt concept]
- Clonal Immunoglobulin Lambda Light Chain Gene Rearrangement [NCIt concept]
disease_has_normal_cell_origin
- B-Lymphocyte [NCIt concept]
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Lymphocyte [NCIt concept]
- Mature B-Lymphocyte [NCIt concept]
- Postgerminal Center B-Lymphocyte of Unknown Differentiation Stage [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
- Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Bone Marrow [NCIt concept]
- Hematopoietic and Lymphatic System [NCIt concept]
- Lymphatic System [NCIt concept]
disease_mapped_to_gene
- BRAF Gene [NCIt concept]
disease_may_have_associated_disease
- Opportunistic Infection [NCIt concept]
- Vasculitis [NCIt concept]
disease_may_have_molecular_abnormality
- CCND1 Protein Overexpression [NCIt concept]
pathogenesis_of_disease_involves_gene
- BRAF Gene [NCIt concept]
- BRAF wt Allele [NCIt concept]

Keyword's position in hierarchy(ies) :

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