NCIt definition : A humanized monoclonal antibody directed against the cell surface receptor CD30 with
potential immunotherapeutic activity. Anti-CD30 monoclonal antibody XmAb2513 specifically
binds to the CD30 antigen, which may result in a cytotoxic T lymphocyte (CTL) response
against CD30-expressing tumor cells. CD30, a member of the tumor necrosis factor (TNF)
receptor superfamily, is expressed on activated lymphocytes transiently and is constitutively
expressed in hematologic malignancies including Hodgkin's disease and some T-cell
non-Hodgkin's lymphomas.;