Bisnafide - CISMeF

Preferred Label : Bisnafide;

NCIt definition : A bis-naphthalimide compound with anticancer activity. Bisnafide selectively intercalates guanine-cytosine (GC) rich regions of DNA, thereby interfering with DNA replication machinery and activity of topoisomerase II. As a result, this agent causes potent cytotoxicity.;

UNII : 62H4W26906;

InChIKey : PXBZKHOQHTVCSQ-QZTJIDSGSA-N;

CAS number : 144849-63-8; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 144849-63-8 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : DMP 840;

Chemical formula : C32H28N6O8;

Details

Origin ID

C73611;

UMLS CUI

C0250021;

Currated CISMeF NLP mapping
- bisnafide [MeSH concept]
- bisnafide [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- bisnafide [MeSH concept]
- bisnafide [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_salt_form
- Bisnafide Dimesylate [NCIt concept]
is_free_acid_or_base_form_of
- Bisnafide Dimesylate [NCIt concept]

Keyword's position in hierarchy(ies) :

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