Bisnafide Dimesylate

Preferred Label : Bisnafide Dimesylate;

NCIt definition : The dimesylate salt form of bisnafide, a bis-naphthalimide compound with anticancer activity. Bisnafide selectively intercalates guanine-cytosine (GC) rich regions of DNA, thereby interfering with DNA replication machinery and activity of topoisomerase II. As a result, this agent causes potent cytotoxicity.;

UNII : J30IBO0LMA;

InChIKey : KPQJSSLKKBKWEW-RKDOVGOJSA-N;

CAS number : 145124-30-7;

Chemical formula : C32H28N6O8.2CH4O3S;

Details

Origin ID

C73307;

UMLS CUI

C2347031;

Semantic type(s)
- Pharmacologic Substance [UMLS semantic type]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_free_acid_or_base_form
- Bisnafide [NCIt concept]
is_salt_form_of
- Bisnafide [NCIt concept]

Keyword's position in hierarchy(ies) :

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