" /> Pentamidine - CISMeF





Preferred Label : Pentamidine;

NCIt synonyms : Aerosolized Pentamadine;

NCIt definition : A synthetic derivative of amidine with antiprotozoal and antifungal activities. Although the precise mode of action of pentamidine is unclear, it appears to interact directly with the pathogen genome by binding to AT-rich regions of duplex DNA and the minor groove of DNA, thereby interfering with DNA replication. (NCI04);

Alternative definition : NCI-GLOSS: The active ingredient in a drug used to treat infections caused by certain microorganisms. It is also being studied in the treatment of melanoma. It prevents DNA from being copied and may kill cancer cells. It is a type of antifungal agent, a type of antiprotozoal agent, and a type of PRL phosphatase inhibitor.;

UNII : 673LC5J4LQ;

InChIKey : XDRYMKDFEDOLFX-UHFFFAOYSA-N;

CAS number : 100-33-4;

Chemical formula : C19H24N4O2;

NSC code : 9921;

ChEBI ID : CHEBI:45081;

Codes from synonyms : CDR0000630950; NSC0009921; 396;

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Keyword's position in hierarchy(ies) : arborescence

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06/05/2025


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