" /> Pentamidine Isethionate - CISMeF





Preferred Label : Pentamidine Isethionate;

NCIt related terms : Pentam;

NCIt definition : A synthetic amidine derivative, Pentamidine Isethionate is an antiprotozoal and antifungal agent that appears to interact with the minor groove of AT-rich DNA regions of the pathogen genome, interfering with DNA replication and function. It is effective in the treatment of trypanosomiasis, leishmaniasis, some fungal infections, and Pneumocystis carinii pneumonia in HIV-infected patients. (NCI04);

Alternative definition : NCI-GLOSS: A drug used to treat infections caused by certain microorganisms. It is also being studied in the treatment of melanoma. It prevents DNA from being copied and may kill cancer cells. It is a type of antifungal agent, a type of antiprotozoal agent, and a type of PRL phosphatase inhibitor.;

UNII : V2P3K60DA2;

InChIKey : YBVNFKZSMZGRAD-UHFFFAOYSA-N;

CAS number : 140-64-7;

Drug name : Pentacarinat; Pentam;

Chemical formula : C19H24N4O2.2C2H6O4S;

NSC code : 620107;

ChEBI ID : CHEBI:7977;

Codes from synonyms : CDR0000630952; CDR0000630954;

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11/05/2025


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