Perindopril - CISMeF

Preferred Label : Perindopril;

NCIt synonyms : (2S,3aS,7aS)-1-((S)-N-((S)-1-Carboxybutyl)alanyl)hexahydro-2-indolinecarboxylic Acid, 1-ethyl Ester;

NCIt definition : A non-sulfhydryl angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. Upon hydrolysis, perindopril is converted to its active form perindoprilat, inhibiting ACE and the conversion of angiotensin I to angiotensin II; consequently, angiotensin II-mediated vasoconstriction and angiotensin II-stimulated aldosterone secretion from the adrenal cortex are inhibited and diuresis and natriuresis ensue.;

UNII : Y5GMK36KGY;

InChIKey : IPVQLZZIHOAWMC-QXKUPLGCSA-N;

CAS number : 82834-16-0;

Molecule name : S-9490;

Chemical formula : C19H32N2O5;

ChEBI ID : CHEBI:8024;

Details

Origin ID

C72910;

UMLS CUI

C0136123;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Perindopril [ICD-11 Extension code]
- Perindopril (substance) [SNOMED CT concept]
- Product containing perindopril (medicinal product) [SNOMED CT concept]
- perindopril [ATC Code]
- perindopril [Substance BNPC]
- perindopril [MeSH concept]
- perindopril [MeSH Descriptor]
Validated automatic mappings to BTNT
- perindopril [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Perindopril Erbumine [NCIt concept]
is_free_acid_or_base_form_of
- Perindopril Erbumine [NCIt concept]

Keyword's position in hierarchy(ies) :

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