" /> Imidapril - CISMeF





Preferred Label : Imidapril;

NCIt synonyms : (S)-3-(N-((S)-1-Ethoxycarbonyl-3-phenylpropyl)-L-alanyl)-1-methyl-2-oxoimidazoline-4-carboxylic acid;

NCIt definition : An angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. As a prodrug, imidapril is converted by hydrolysis in the liver into its active form imidaprilat. Imidaprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II and results in vasodilation. Imidaprilat also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow.;

UNII : BW7H1TJS22;

InChIKey : KLZWOWYOHUKJIG-BPUTZDHNSA-N;

CAS number : 89371-37-9;

Chemical formula : C20H27N3O6;

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08/05/2025


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