Valopicitabine Dihydrochloride

Preferred Label : Valopicitabine Dihydrochloride;

NCIt definition : The dihydrochloride salt of valopicitabine, a 3-O-valine ester prodrug form of the nucleoside analog 2'-C-methylcytidine with anti-hepatitis C virus (HCV) activity. Upon administration, valopicitabine is converted into 2'-C-methylcytidine; upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and viral RNA-dependent RNA polymerase activity. This blocks viral production of HCV RNA and thus viral replication.;

UNII : 7KNU786IT4;

InChIKey : XENHXZMAOSTXGD-DSMKLBDQSA-N;

CAS number : 640725-71-9;

Molecule name : NM-283;

Chemical formula : C15H24N4O6.2ClH;

Détails

Origin ID

C72874;

UMLS CUI

C2349102;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
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- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
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- Valopicitabine [NCIt concept]
is_salt_form_of
- Valopicitabine [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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