Piroxantrone Hydrochloride

Preferred Label : Piroxantrone Hydrochloride;

NCIt definition : The hydrochloride salt form of piroxantrone, an anthrapyrazole antineoplastic antibiotic. Piroxantrone intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair as well as RNA and protein synthesis. Although less cardiotoxic than doxorubicin, this agent exhibits a narrow spectrum of antineoplastic activity.;

UNII : PS51OZG63Z;

InChIKey : PPASFTRHCXASPY-UHFFFAOYSA-N;

CAS number : 105118-12-5;

Chemical formula : C21H25N5O4.2HCl;

Details

Origin ID

C72829;

UMLS CUI

C1522210;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_free_acid_or_base_form
- Piroxantrone [NCIt concept]
is_salt_form_of
- Piroxantrone [NCIt concept]

Keyword's position in hierarchy(ies) :

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