Batabulin - CISMeF

Preferred Label : Batabulin;

NCIt synonyms : 2-Fluoro-1-methoxy-4-pentafluorophenylsulfonamidobenzene;

NCIt related terms : T138067;

NCIt definition : A synthetic pentafluorophenylsulfonamide with potential antineoplastic activity. Batabulin covalently binds to beta tubulin, resulting in a disruption of microtubule polymerization, collapse of the cytoskeleton, cell cycle arrest, and tumor cell apoptosis.;

Alternative definition : NCI-GLOSS: An anticancer drug that belongs to the family of drugs called mitotic inhibitors. It inhibits the growth of cancer cells by preventing cell division.;

UNII : T4NP8G3K6Q;

InChIKey : ROZCIVXTLACYNY-UHFFFAOYSA-N;

CAS number : 195533-53-0;

Chemical formula : C13H7F6NO3S;

Codes from synonyms : CDR0000046096;

Details

Origin ID

C72716;

UMLS CUI

C0767920;

Automatic exact mappings (from CISMeF team)
- batabulin [MeSH Supplementary Concept]
Currated CISMeF NLP mapping
- batabulin [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- batabulin [MeSH Supplementary Concept]
- batabulin [MeSH concept]
chemical_or_drug_has_mechanism_of_action
- Microtubule Process [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_salt_form
- Batabulin Sodium [NCIt concept]
is_free_acid_or_base_form_of
- Batabulin Sodium [NCIt concept]

Keyword's position in hierarchy(ies) :

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