Preferred Label : Batabulin Sodium;
NCIt synonyms : 2-Fluoro-1-methoxy-4-(pentafluorophenyl-sulfonamido)benzene, Sodium Salt; T138067;
NCIt definition : The sodium salt form of batabulin, a synthetic pentafluorophenylsulfonamide with potential
antineoplastic activity. Batabulin covalently binds to and selectively modifies the
beta 1, beta 2, beta 3, and beta 4 isotypes of beta tubulin at a conserved cysteine
residue, resulting in disruption of microtubule polymerization, collapse of the cytoskeleton,
an increase in chromosomal ploidy, cell cycle arrest, and tumor cell apoptosis.;
UNII : G04B77F772;
InChIKey : UWPXRVDIKGZQQW-UHFFFAOYSA-N;
CAS number : 195533-98-3; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 195533-98-3
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G-SRS /a ;
Molecule name : T138067 Sodium;
Chemical formula : C13H6F6NO3S.Na;
Origin ID : C1835;
UMLS CUI : C1523985;
Automatic exact mappings (from CISMeF team)
- Semantic type(s)
- chemical_or_drug_has_mechanism_of_action
- concept_is_in_subset
- has_free_acid_or_base_form
- is_salt_form_of
