Anamorelin Hydrochloride

Preferred Label : Anamorelin Hydrochloride;

NCIt synonyms : RC-1291 HCl;

NCIt definition : The orally bioavailable hydrochloride salt of a synthetic, small-molecule ghrelin mimetic with appetite-stimulating and anabolic activities. Anamorelin binds to and stimulates the growth hormone secretagogue receptor (GHSR) centrally, thereby mimicking the appetite-stimulating and growth hormone-releasing effects of grhelin. Stimulation of GHSR may also reduce the production of the pro-inflammatory cytokines TNF-alpha and interleukin-6, which may play a direct role in cancer-related loss of appetite.;

UNII : 55F75LJQ0V;

InChIKey : VFYAEUWJFGTGGO-GHTUPXNNSA-N;

CAS number : 861998-00-7;

Chemical formula : C31H42N6O3.ClH;

Details

Origin ID

C72701;

UMLS CUI

C2346777;

Currated CISMeF NLP mapping
- anamorelin hydrochloride [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- anamorelin hydrochloride [MeSH concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_free_acid_or_base_form
- Anamorelin [NCIt concept]
is_salt_form_of
- Anamorelin [NCIt concept]

Keyword's position in hierarchy(ies) :

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