Anamorelin - CISMeF

Preferred Label : Anamorelin;

NCIt synonyms : RC-1291 Ghrelin Mimetic;

NCIt definition : A synthetic, orally bioavailable, small-molecule ghrelin mimetic with appetite-stimulating and anabolic activities. Anamorelin binds to and stimulates the growth hormone secretagogue receptor (GHSR) centrally, thereby mimicking the appetite-stimulating and growth hormone-releasing effects of ghrelin. Stimulation of GHSR may also reduce the production of the pro-inflammatory cytokines TNF-alpha and interleukin-6, which may play a direct role in cancer-related loss of appetite.;

UNII : DD5RBA1NKF;

InChIKey : VQPFSIRUEPQQPP-MXBOTTGLSA-N;

CAS number : 249921-19-5;

Molecule name : RC-1291;

Chemical formula : C31H42N6O3;

Details

Origin ID

C52197;

UMLS CUI

C2698934;

Currated CISMeF NLP mapping
- anamorelin [MeSH concept]
- anamorelin [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Hormone [UMLS semantic type]
UMLS correspondences (same concept)
- anamorelin [MeSH concept]
- anamorelin [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Anamorelin Hydrochloride [NCIt concept]
is_free_acid_or_base_form_of
- Anamorelin Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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