Tapentadol - CISMeF

Preferred Label : Tapentadol;

NCIt definition : An orally available, synthetic benzenoid that acts as an agonist for the mu-opioid receptor (MOR) and inhibits the reuptake of noradrenaline, with potential anti-nociceptive activity. Upon oral administration, tapentadol binds to the MOR which enhances MOR-mediated signaling, interferes with the sensation of pain and results in an analgesic effect. Tapentadol also inhibits the reuptake of noradrenaline, which increases the levels of noradrenaline (NA), activates the inhibitory alpha-2 receptors and results in an analgesic effect.;

UNII : H8A007M585;

InChIKey : KWTWDQCKEHXFFR-SMDDNHRTSA-N;

CAS number : 175591-23-8;

Chemical formula : C14H23NO;

Details

Origin ID

C72139;

UMLS CUI

C2001271;

Currated CISMeF NLP mapping
- Tapentadol [LOINC component]
- Tapentadol [MeSH Descriptor]
- Tapentadol [ICD-11 Extension code]
- Tapentadol [SMS substance]
- Tapentadol (substance) [SNOMED CT concept]
- tapentadol [MeSH concept]
See also inter- (CISMeF)
- Product containing tapentadol (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing tapentadol (medicinal product) [SNOMED CT concept]
- Tapentadol [LOINC component]
- Tapentadol [MeSH Descriptor]
- Tapentadol (substance) [SNOMED CT concept]
- tapentadol [ATC Code]
- tapentadol [MeSH concept]
Validated automatic mappings to BTNT
- tapentadol [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Tapentadol Hydrochloride [NCIt concept]
is_free_acid_or_base_form_of
- Tapentadol Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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