" /> Losoxantrone Hydrochloride - CISMeF





Preferred Label : Losoxantrone Hydrochloride;

NCIt synonyms : Losoxantrone HCl; Losoxantrone Hydrochloride Hydrate;

NCIt definition : The hydrochloride salt form of losoxantrone, an anthrapyrazole-based antineoplastic antibiotic. Losoxantrone intercalates into DNA, induces single- and double-stranded DNA breaks and inhibits topoisomerase II, thereby inhibiting DNA replication and repair as well as RNA and protein synthesis. Losoxantrone is less cardiotoxic than doxorubicin.;

UNII : W6E275IURX;

InChIKey : CNQCTSLNJJVSAU-UHFFFAOYSA-N;

CAS number : 132937-89-4;

Chemical formula : 2C22H27N5O4.4ClH.H2O;

NSC code : 357885;

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08/05/2025


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