NCIt definition : The hydrochloride salt form of losoxantrone, an anthrapyrazole-based antineoplastic
antibiotic. Losoxantrone intercalates into DNA, induces single- and double-stranded
DNA breaks and inhibits topoisomerase II, thereby inhibiting DNA replication and repair
as well as RNA and protein synthesis. Losoxantrone is less cardiotoxic than doxorubicin.;
UNII : W6E275IURX;
InChIKey : CNQCTSLNJJVSAU-UHFFFAOYSA-N;
CAS number : 132937-89-4; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 132937-89-4
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Semantic type(s)