NCIt definition : An anthrapyrazole-based antineoplastic antibiotic. Losoxantrone intercalates into
DNA, induces single- and double-stranded DNA breaks and inhibits topoisomerase II,
thereby inhibiting DNA replication and repair as well as RNA and protein synthesis.
Losoxantrone is less cardiotoxic than doxorubicin.;
Alternative definition : NCI-GLOSS: An anticancer drug that belongs to the family of drugs called antipyrazoles.;
UNII : 47KPH00809;
InChIKey : YROQEQPFUCPDCP-UHFFFAOYSA-N;
CAS number : 88303-60-0; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 88303-60-0
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