" /> Losoxantrone - CISMeF





Preferred Label : Losoxantrone;

NCIt synonyms : Biantrazole;

NCIt related terms : CI-941;

NCIt definition : An anthrapyrazole-based antineoplastic antibiotic. Losoxantrone intercalates into DNA, induces single- and double-stranded DNA breaks and inhibits topoisomerase II, thereby inhibiting DNA replication and repair as well as RNA and protein synthesis. Losoxantrone is less cardiotoxic than doxorubicin.;

Alternative definition : NCI-GLOSS: An anticancer drug that belongs to the family of drugs called antipyrazoles.;

UNII : 47KPH00809;

InChIKey : YROQEQPFUCPDCP-UHFFFAOYSA-N;

CAS number : 88303-60-0;

Molecule name : DuP 941; CI-941;

Chemical formula : C22H27N5O4;

Codes from synonyms : CDR0000045401; NSC0357885;

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28/07/2025


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