" /> Enzalutamide - CISMeF





Preferred Label : Enzalutamide;

NCIt synonyms : Benzamide, 4-(3-(4-cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl)-2-fluoro-N-methyl-; Selective Androgen Receptor Modulator MDV3100;

NCIt definition : An orally bioavailable, organic, non-steroidal small molecule targeting the androgen receptor (AR) with potential antineoplastic activity. Through a mechanism that is reported to be different from other approved AR antagonists, enzalutamide inhibits the activity of prostate cancer cell ARs, which may result in a reduction in prostate cancer cell proliferation and, correspondingly, a reduction in the serum prostate specific antigen (PSA) level. AR over-expression in prostate cancer represents a key mechanism associated with prostate cancer hormone resistance.;

UNII : 93T0T9GKNU;

InChIKey : WXCXUHSOUPDCQV-UHFFFAOYSA-N;

CAS number : 915087-33-1;

Drug name : Xtandi;

Molecule name : MDV-3100; ASP9785; MDV 3100;

Chemical formula : C21H16F4N4O2S;

Codes from synonyms : 189;

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07/05/2025


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