" /> Apomab - CISMeF





Preferred Label : Apomab;

NCIt definition : A fully human monoclonal antibody directed against human death receptor 5 (DR5; TRAIL-R2; TNFRSF10B) with potential pro-apoptotic and antineoplastic activities. Mimicking the natural ligand TRAIL (tumor necrosis factor-related apoptosis inducing ligand), apomab binds to DR5, which may directly activate the extrinsic apoptosis pathway and indirectly induce the intrinsic apoptosis pathway in tumor cells. DR5 is a cell surface receptor of the TNF-receptor superfamily and is expressed in a broad range of cancers.;

UNII : 703KLX5LXZ;

CAS number : 1108170-71-3; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 1108170-71-3 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

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15/05/2024


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