" /> Biricodar - CISMeF





Preferred Label : Biricodar;

NCIt definition : A pipecolinate derivative. Functioning as a modulator of P-glycoprotein (P-gp) and multidrug resistance protein (MRP-1), biricodar restores drug sensitivity to cells expressing P-glycoprotein and MRP1, the cellular efflux pumps that are the major causes in tumor cell resistance to chemotherapeutic agents. This agent binds directly to Pgp and MRP-1 and inhibits efflux pump activity, resulting in increased intracellular accumulation and retention of cytotoxic agents.;

UNII : 3KG76X4KJK;

InChIKey : CGVWPQOFHSAKRR-NDEPHWFRSA-N;

CAS number : 159997-94-1;

Molecule name : VX-710;

Chemical formula : C34H41N3O7;

Détails


Vous pouvez consulter :


Nous contacter.
31/07/2025


[Accueil] [Haut de page]

© CHU de Rouen. Toute utilisation partielle ou totale de ce document doit mentionner la source.