Anti-PSCA Monoclonal Antibody AGS-1C4D4

Preferred Label : Anti-PSCA Monoclonal Antibody AGS-1C4D4;

NCIt synonyms : Monoclonal Antibody MK4721;

NCIt related terms : MK-4721;

NCIt definition : An IgG1k fully human monoclonal antibody directed against the human prostate stem cell antigen (PSCA) with potential antineoplastic activity. Anti-PSCA fully human monoclonal antibody MK4721 selectively targets and binds to PSCA, triggering complement-dependent cell lysis and antibody-dependent cell-mediated cytotoxicity in tumor cells expressing PSCA. PSCA is a glycosyl-phosphatidylinositol (GPI)-linked cell surface antigen found in cancers of the bladder, pancreas, and prostate.;

UNII : L0505LPC7O;

Molecule name : MK4721; AGS-1C4D4;

Details

Origin ID

C71157;

UMLS CUI

C2347292;

Currated CISMeF NLP mapping
- AGS-1C4D4 [MeSH concept]
See also inter- (CISMeF)
- MK-4721 [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- AGS-1C4D4 [MeSH concept]
- MK-4721 [MeSH Supplementary Concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Binding [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Prostate Stem Cell Antigen [NCIt concept]

Keyword's position in hierarchy(ies) :

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