" /> Magnesium Valproate - CISMeF





Preferred Label : Magnesium Valproate;

NCIt synonyms : Valproate Magnesium; Magnesium Dipropylacetate; Pentanoic acid, 2-propyl-, Magnesium Salt;

NCIt definition : The magnesium salt of valproic acid (2-propylpentanoic acid) with antiepileptic and potential antineoplastic activities. Magnesium valproate dissociates in the gastrointestinal tract and is absorbed into the circulation as magnesium ions and valproic acid ions; valproic acid may inhibit histone deacetylases, inducing tumor cell differentiation, apoptosis, and growth arrest. In addition, valproic acid exerts an antiepileptic effect, likely by inhibiting enzymes that catabolize the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) catabolism and so increasing concentrations of GABA in the central nervous system (CNS). The presence of the magnesium in this agent may contribute to its anticonvulsant activity and sedative properties.;

UNII : Q400352CM2;

InChIKey : LKLLHOIUJVEAGU-UHFFFAOYSA-L;

CAS number : 62959-43-7; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 62959-43-7 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Chemical formula : 2C8H15O2.Mg;

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15/05/2024


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