Preferred Label : Salirasib;
NCIt synonyms : S-Farnesylthiosalicylic Acid; 2-(((2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrienyl)sulfanyl)benzoic Acid;
NCIt definition : A salicylic acid derivative with potential antineoplastic activity. Salirasib dislodges
all Ras isoforms from their membrane-anchoring sites, thereby preventing activation
of RAS signaling cascades that mediated cell proliferation, differentiation, and senescence.
RAS signaling is believed to be abnormally activated in one-third of human cancers,
including cancers of the pancreas, colon, lung and breast.;
UNII : MZH0OM550M;
InChIKey : WUILNKCFCLNXOK-CFBAGHHKSA-N;
CAS number : 162520-00-5; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 162520-00-5
alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo
G-SRS /a ;
Chemical formula : C22H30O2S;
Origin ID : C71146;
UMLS CUI : C0297001;
Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to NTBT
- concept_is_in_subset
- has_target
