" /> Recombinant Human EGF-rP64K/Montanide ISA 51 Vaccine - CISMeF





Preferred Label : Recombinant Human EGF-rP64K/Montanide ISA 51 Vaccine;

NCIt synonyms : Center of Molecular Immunology (CIMA) Epidermal Growth Factor (EGF) Vaccine; Recombinant Human EGF-rP64K Montanide ISA 51 Vaccine; CIMAvax EGF; Center of Molecular Immunology Epidermal Growth Factor Vaccine; CIMAvax Epidermal Growth Factor Vaccine; Recombinant Human EGF-P64K/Montanide Vaccine; CIMAvax-EGF; CimaVax; CimaVax Vaccine;

NCIt definition : A peptide vaccine preparation, containing recombinant human epidermal growth factor (rEGF) linked to the Neisseria meningitidis-derived recombinant immunogenic carrier protein P64k (rP64k) and mixed with the immunoadjuvant Montanide ISA 51, with potential active immunotherapy activity. Recombinant human EGF-rP64K/Montanide ISA 51 vaccine may trigger a humoral immune response against vaccine rEGF and rP64K and, so, against endogenous EGF. Antibody-mediated inhibition of endogenous EGF binding to its receptor, epithelial growth factor receptor (EGFR), may result in the inhibition of tumor cell proliferation.;

NCI Metathesaurus CUI : CL376048;

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16/05/2024


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