NCIt synonyms : Total Hemolytic Complement Assay; Total Hemolytic Complement CH50;
NCIt related terms : Total Hemolytic Activity Assay; Total Hemolytic Complement 50%; CH50; HEMOLYTIC COMPLEMENT ACTIVITY ASSAY;
NCIt definition : A screening assay for circulating complement proteins in which diluted serum samples
are added to antibody-coated erythrocytes and the percentage of cell lysis is measured.
The values are expressed in hemolytic complement units per milliliter (CH50), the
dilution of serum required to lyse 50 percent of the erythrocytes in the assay.;
Alternative definition : NICHD: A functional measurement of the ability of serum complement proteins to lyse
target cells via classical activation that measures function of all complement components
C1-C9. The CH50 is the reciprocal of the dilution of serum that induces lysis of 50%
of target cells in a standardized assay.; CDISC: A technique for measuring circulating complement in which biological specimens
are added to antibody-coated erythrocytes and the percentage of cell lysis is measured.;
Currated CISMeF NLP mapping