Preferred Label : complement hemolytic activity assay;
MeSH definition : A screening assay for circulating COMPLEMENT PROTEINS. Diluted SERUM samples are added
to antibody-coated ERYTHROCYTES and the percentage of cell lysis is measured. The
values are expressed by the so called CH50, in HEMOLYTIC COMPLEMENT units per milliliter,
which is the dilution of serum required to lyse 50 percent of the erythrocytes in
the assay.;
MeSH synonym : assay, ch50; assay, hemolytic titration; assays, ch50; assays, hemolytic titration; ch50 assay; ch50 assays; hemolytic titration assay; hemolytic titration assays; titration assay, hemolytic; titration assays, hemolytic;
MeSH hyponym : complement H50; serum complement titer; total hemolytic complement; whole complement titer; Titer, Whole Complement; Titers, Whole Complement; Whole Complement Titers; Complement, Total Hemolytic; Complements, Total Hemolytic; Hemolytic Complement, Total; Hemolytic Complements, Total; Total Hemolytic Complements; Complement H50s; CH(50); Serum Complement Titers; Titer, Serum Complement; Titers, Serum Complement;
Origin ID : D015941;
UMLS CUI : C0373838;
Allowable qualifiers
- Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- Record concept(s)
- See also inter- (CISMeF)
- Semantic type(s)
- UMLS correspondences (same concept)
A screening assay for circulating COMPLEMENT PROTEINS. Diluted SERUM samples are added
to antibody-coated ERYTHROCYTES and the percentage of cell lysis is measured. The
values are expressed by the so called CH50, in HEMOLYTIC COMPLEMENT units per milliliter,
which is the dilution of serum required to lyse 50 percent of the erythrocytes in
the assay.
