NCIt definition : An orally active, selective MEK inhibitor with potential antineoplastic activity.
MEK inhibitor AZD8330 specifically inhibits mitogen-activated protein kinase kinase
1 (MEK or MAP/ERK kinase1), resulting in inhibition of growth factor-mediated cell
signaling and tumor cell proliferation. MEK is a key component of the RAS/RAF/MEK/ERK
signaling pathway that regulates cell growth; constitutive activation of this pathway
has been implicated in many cancers.;
UNII : G4990BOZ66;
CAS number : 869357-68-6; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 869357-68-6
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