IL21R wt Allele

Preferred Label : IL21R wt Allele;

NCIt synonyms : IL21R; Interleukin 21 Receptor wt Allele; UNQ3121/PRO10273; NILR; CD360; IMD56;

NCIt definition : Human IL21R wild-type allele is located in the vicinity of 16p11 and is approximately 48 kb in length. This allele, which encodes interleukin-21 receptor protein, is involved in the regulation of cytokine signaling. A translocation t(3;7)(q27;p12) that fuses the gene to the BCL6 gene is implicated in diffuse large B-cell lymphomas.;

GenBank Accession Number : NM_181078;

Details

Origin ID

C68737;

UMLS CUI

C2346455;

OMIM relation
- Interleukin 21 receptor [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 16p11 [NCIt concept]
gene_is_element_in_pathway
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- Jak-STAT Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Interleukin Signaling Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]

Keyword's position in hierarchy(ies) :

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