" /> Childhood B Acute Lymphoblastic Leukemia with t(9;22)(q34.1;q11.2); BCR-ABL1 - CISMeF





Preferred Label : Childhood B Acute Lymphoblastic Leukemia with t(9;22)(q34.1;q11.2); BCR-ABL1;

NCIt synonyms : Philadelphia Positive Childhood Acute Lymphoblastic Leukemia; Childhood B-Cell Acute Lymphoblastic Leukemia with t(9;22)(q34;q11.2); BCR-ABL1; Philadelphia Positive Childhood Precursor Lymphoblastic Leukemia; Childhood B Acute Lymphoblastic Leukemia with t(9;22)(q34.1;q11.2); BCR::ABL1;

NCIt related terms : B Acute Lymphoblastic Leukemia with t(9;22)(q34.1;q11.2); BCR-ABL1; Philadelphia-Positive ALL; Childhood B Acute Lymphoblastic Leukemia with t(9;22)(q34;q11.2); BCR-ABL1;

NCIt definition : A B acute lymphoblastic leukemia that occurs during childhood. It is characterized by the presence of lymphoblasts that carry a translocation between the BCR gene on chromosome 22 and the ABL1 gene on chromosome 9. It results in the production of the p190 kd or p210 kd fusion protein. It has an unfavorable clinical outcome.;

Alternative definition : NICHD: Acute lymphoblastic leukemia occurring during childhood that is characterized by the presence of the Philadelphia chromosome t(9;22), which leads to production of a BCR-ABL1 fusion protein with tyrosine kinase activity.;

Neoplastic status : Malignant;

NCI Metathesaurus CUI : CL374485;

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30/04/2024


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