Mannose-Binding Protein C

Preferred Label : Mannose-Binding Protein C;

NCIt synonyms : Mannan-Binding Protein; Mannose Binding Protein; Mannan-Binding Lectin; MBP-C; MBP; MBP1; MBL; Mannose-Binding Lectin;

NCIt definition : Mannose-binding protein C (248 aa, 26 kDa) is encoded by the human MBL2 gene. This protein plays a role in the initiation of targeted host defense mechanisms against pathogens by activating the complement pathway.;

NCIt note : The MBL2 gene product can be produced recombinantly and is used therapeutically to treat patients that are deficient for this gene.;

Details

Origin ID

C68581;

UMLS CUI

C0526870;

Currated CISMeF NLP mapping
- MBL2 protein, human [MeSH concept]
- MBL2 protein, human [MeSH Supplementary Concept]
OMIM relation
- Mannose-binding lectin 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- MBL2 protein, human [MeSH concept]
- MBL2 protein, human [MeSH Supplementary Concept]
Validated automatic mappings to NTBT
- Mannose-binding protein (substance) [SNOMED CT concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- NCIt COVID-19 Clinical Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
gene_encodes_gene_product
- Immunoprotein Gene [NCIt concept]
- MBL2 Gene [NCIt concept]
gene_product_plays_role_in_biological_process
- Immune System Process [NCIt concept]
is_target
- Technetium Tc 99m-labeled Tilmanocept [NCIt concept]

Keyword's position in hierarchy(ies) :

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