NCIt definition : An enediyne antineoplastic antibiotic hybrid containing an aminoglycoside chromophore.
Zinostatin is isolated from the bacterium Streptomyces carzinostaticus. The aminoglycoside
component of zinostatin intercalates into DNA and the benzene diradical intermediate
of the enediyne core binds to the minor groove of DNA, resulting in single- and double-strand
breaks in DNA and apoptosis. (NCI04);
UNII : PP082U6W1L;
CAS number : 9014-02-2; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 9014-02-2
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