Nafoxidine - CISMeF

Preferred Label : Nafoxidine;

NCIt synonyms : NFX;

NCIt definition : A triphenylethylene nonsteroidal agent that acts as a partial estrogen antagonist. Nafoxidine competes with endogenous estrogen for binding to specific estrogen receptors. This agent also inhibits angiogenesis in some tissues by blocking the effects of fibroblast growth factor (FGF) and vascular endothelial growth factor (VEGF); paradoxically, it may enhance angiogenesis in uterine tissue. Nafoxidine also induces oxidative stress, protein kinase C and calcium signaling. (NCI04);

UNII : 4RIY10WM82;

InChIKey : JEYWNNAZDLFBFF-UHFFFAOYSA-N;

CAS number : 1845-11-0;

Chemical formula : C29H31NO2;

Details

Origin ID

C677;

UMLS CUI

C0027328;

Automatic exact mappings (from CISMeF team)
- Nafoxidine [ICHI extension code]
Currated CISMeF NLP mapping
- Nafoxidine [ICD-11 Extension code]
- Nafoxidine (substance) [SNOMED CT concept]
- nafoxidine [MeSH Descriptor]
- nafoxidine [MeSH concept]
- nafoxidine [SNOMED Notion]
See also inter- (CISMeF)
- Product containing nafoxidine (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Nafoxidine [ICD-11 Extension code]
- Nafoxidine (substance) [SNOMED CT concept]
- Product containing nafoxidine (medicinal product) [SNOMED CT concept]
- nafoxidine [MeSH concept]
- nafoxidine [MeSH Descriptor]
- nafoxidine [SNOMED Notion]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Nafoxidine Hydrochloride [NCIt concept]
is_free_acid_or_base_form_of
- Nafoxidine Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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