NCIt definition : Human NAT2*5 allele is a designation for a group of variant alleles of the NAT2 gene,
which is located in the vicinity of 8p22 and is approximately 10 kb in length. The
wild-type allele, which encodes arylamine N-acetyltransferase 2 protein, is involved
in the activation/deactivation of arylamine and hydrazine compounds. This group of
allelic variants of the NAT2 gene all exhibit a SNP (c. 341T C) that results in a
I114T coding change and is associated with decreased enzymatic activity of the encoded
protein.;