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Synthetic Peptides E-PRA And E-PSM Vaccine - CISMeF
Synthetic Peptides E-PRA And E-PSM VaccineNCIt concept
Preferred Label : Synthetic Peptides E-PRA And E-PSM Vaccine;
NCIt synonyms : Synthetic Peptides E-PRA E-PSM;
NCIt definition : A cancer vaccine consisting of E-PRA and E-PSM, two synthetic peptide analogs of PRAME
(PReferential Antigen MElanoma) and PSMA (Prostate Specific Membrane Antigen), with
potential immunostimulating activity. Upon direct administration into lymph nodes,
synthetic peptides E-PRA and E-PSM vaccine may stimulate a cytotoxic T-lymphocyte
(CTL) response against PRAME- and PSMA-expressing tumor cells. PRAME and PSMA are
tumor-associated antigens upregulated and expressed on the cell surfaces of certain
tumor cell types.;
NCIt note : Part of the MKC1106-PP regimen together with PRA-PSM-Expressing Plasmid;
Semantic type(s)