Aurora Kinase Inhibitor PF-03814735

Preferred Label : Aurora Kinase Inhibitor PF-03814735;

NCIt related terms : PF-03814735;

NCIt definition : An aurora kinase inhibitor with potential antineoplastic activity. PF-03814735 binds to and inhibits aurora kinases, serine-threonine kinases that play essential roles in mitotic checkpoint control during mitosis. Inhibition of aurora kinases may result in an inhibition of cellular division and proliferation in tumor cells that overexpress aurora kinases.;

UNII : 6V5T4O5758;

CAS number : 942487-16-3;

Molecule name : PF-03814735;

Details

Origin ID

C66946;

UMLS CUI

C1882256;

CISMeF manual mappings
- PF 03814735 [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- PF 03814735 [MeSH concept]
chemical_or_drug_affects_gene_product
- Aurora Kinase A [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Aurora Kinase A [NCIt concept]
- Aurora Kinase B [NCIt concept]

Keyword's position in hierarchy(ies) :

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