NCIt definition : The hydrochloride salt form of phenylpropanolamine, an alpha- and beta-adrenergic
receptor agonist with sympathomimetic activity. Phenylpropanolamine binds to and activates
alpha- and beta-adrenergic receptors in the mucosa of the respiratory tract resulting
in vasoconstriction and reduction in swelling of nasal mucous membranes and reduction
in tissue hyperemia, edema, and nasal congestion. This agent also stimulates the release
of norepinephrine from its storage sites resulting in the effects already described.
Finally, phenylpropanolamine indirectly stimulates beta-receptors producing tachycardia
and a positive inotropic effect.;