Phenylpropanolamine

Preferred Label : Phenylpropanolamine;

NCIt definition : An alpha- and beta-adrenergic receptor agonist with sympathomimetic activity. Phenylpropanolamine (PPA) binds to and activates alpha- and beta-adrenergic receptors in the mucosa of the respiratory tract resulting in vasoconstriction and reduction in swelling of nasal mucous membranes and reduction in tissue hyperemia, edema, and nasal congestion. This agent also stimulates the release of norepinephrine from its storage sites resulting in the effects already described. Finally, PPA indirectly stimulates beta-receptors producing tachycardia and a positive inotropic effect.;

UNII : 33RU150WUN;

InChIKey : DLNKOYKMWOXYQA-CBAPKCEASA-N;

CAS number : 492-41-1; 14838-15-4;

Chemical formula : C9H13NO;

NSC code : 9920; 17704;

Details

Origin ID

C29364;

UMLS CUI

C0031495;

Currated CISMeF NLP mapping
- Phenylpropanolamine [ICD-11 Extension code]
- Phenylpropanolamine [LOINC component]
- Phenylpropanolamine [ICHI extension code]
- Phenylpropanolamine (substance) [SNOMED CT concept]
- alcool (r*,s*)-(+-)-.alpha.-(1-aminoethyl)benzylique [nom iupac français], (r*,s*)-(+-)-.alpha.-(1-aminoethyl)benzyl alcohol [Substance BNPC]
- phenyl propanolamine [SNOMED Notion]
- phenylpropanolamine [MeSH Descriptor]
- phenylpropanolamine [MeSH concept]
False automatic mappings
- Product containing phenylpropanolamine (medicinal product) [SNOMED CT concept]
See also inter- (CISMeF)
- Phenylpropanolamine [LOINC component]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Phenylpropanolamine [ICD-11 Extension code]
- Phenylpropanolamine [LOINC component]
- Phenylpropanolamine (substance) [SNOMED CT concept]
- Product containing phenylpropanolamine (medicinal product) [SNOMED CT concept]
- alcool (r*,s*)-(+-)-.alpha.-(1-aminoethyl)benzylique [nom iupac français], (r*,s*)-(+-)-.alpha.-(1-aminoethyl)benzyl alcohol [Substance BNPC]
- phenyl propanolamine [SNOMED Notion]
- phenylpropanolamine [ATC Code]
- phenylpropanolamine [MeSH concept]
- phenylpropanolamine [MeSH Descriptor]
Validated automatic mappings to BTNT
- phenylpropanolamine [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Phenylpropanolamine Bitartrate [NCIt concept]
- Phenylpropanolamine Hydrochloride [NCIt concept]
is_free_acid_or_base_form_of
- Phenylpropanolamine Bitartrate [NCIt concept]
- Phenylpropanolamine Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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