Penbutolol - CISMeF

Preferred Label : Penbutolol;

NCIt definition : A lipophilic, nonselective beta-adrenergic receptor antagonist with anti-anginal and antihypertensive activities. Penbutolol competitively binds to and blocks beta-1 adrenergic receptors in the heart, thereby decreasing cardiac contractility and rate. This leads to a reduction in cardiac output and lowers blood pressure. In addition, penbutolol prevents the release of renin, a hormone secreted by the kidneys that causes constriction of blood vessels.;

UNII : 78W62V43DY;

InChIKey : KQXKVJAGOJTNJS-HNNXBMFYSA-N;

CAS number : 38363-40-5;

Chemical formula : C18H29NO2;

ChEBI ID : CHEBI:7954;

Details

Origin ID

C66336;

UMLS CUI

C0030812;

Automatic exact mappings (from CISMeF team)
- Penbutolol [ICHI extension code]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- 1-(tert-butylamino)-3-(o-cyclopentylphenoxy)propan-2-ol [Substance BNPC]
- Penbutolol [ICD-11 Extension code]
- Penbutolol (substance) [SNOMED CT concept]
- Product containing penbutolol (medicinal product) [SNOMED CT concept]
- penbutolol [ATC Code]
- penbutolol [MeSH concept]
- penbutolol [MeSH Descriptor]
Validated automatic mappings to BTNT
- 1-(tert-butylamino)-3-(o-cyclopentylphenoxy)propan-2-ol [Substance BNPC]
- penbutolol [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Penbutolol Sulfate [NCIt concept]
is_free_acid_or_base_form_of
- Penbutolol Sulfate [NCIt concept]

Keyword's position in hierarchy(ies) :

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