Penbutolol Sulfate

Preferred Label : Penbutolol Sulfate;

NCIt definition : The sulfate salt form of penbutolol, a lipophilic, nonselective beta-adrenergic receptor antagonist with anti-anginal and antihypertensive activities. Penbutolol competitively binds to and blocks beta-1 adrenergic receptors in the heart, thereby decreasing cardiac contractility and rate. This leads to a reduction in cardiac output and lowers blood pressure. In addition, bisoprolol prevents the release of renin, a hormone secreted by the kidneys that causes constriction of blood vessels.;

UNII : US71433228;

InChIKey : FEDSNBHHWZEYTP-ZFQYHYQMSA-N;

CAS number : 38363-32-5;

Drug name : Levatol;

Chemical formula : 2C18H29NO2.H2SO4;

ChEBI ID : CHEBI:7955;

Détails

Origin ID

C61882;

UMLS CUI

C0282292;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- (S)-Bis(di-tert-butyl(3-(2-cyclopentylphenoxy)-2-hydroxypropyl)ammonium) sulphate [Substance BNPC]
- Penbutolol sulfate (substance) [SNOMED CT concept]
- penbutolol sulfate [MeSH concept]
Validated automatic mappings to NTBT
- penbutolol [MeSH Descriptor]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_free_acid_or_base_form
- Penbutolol [NCIt concept]
is_salt_form_of
- Penbutolol [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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