NCIt definition : A lipophilic, nonselective beta-adrenergic receptor antagonist with anti-arrhythmic,
anti-anginal and antihypertensive activities. Oxprenolol competitively binds to and
blocks beta-1 adrenergic receptors in the heart, thereby decreasing cardiac contractility
and rate. This leads to a reduction in cardiac output and lowers blood pressure. In
addition, oxprenolol prevents the release of renin, a hormone secreted by the kidneys
that causes constriction of blood vessels.;