Olmesartan - CISMeF

Preferred Label : Olmesartan;

NCIt definition : A synthetic imidazole derivative and angiotensin II receptor antagonist with antihypertensive activity. Olmesartan selectively binds to the angiotensin type 1 (AT1) receptor subtype in vascular smooth muscle and adrenal gland, thereby competing with angiotensin II for binding to the AT1 receptor. This prevents angiotensin II-induced vasoconstriction and interferes with angiotensin II-mediated aldosterone secretion, thereby decreasing aldosterone production and preventing aldosterone-stimulated sodium retention and potassium excretion.;

UNII : 8W1IQP3U10;

InChIKey : VTRAEEWXHOVJFV-UHFFFAOYSA-N;

CAS number : 144689-24-7;

Chemical formula : C24H26N6O3;

ChEBI ID : CHEBI:48416;

Details

Origin ID

C66253;

UMLS CUI

C1098320;

Currated CISMeF NLP mapping
- Olmesartan [SMS substance]
- Olmesartan (substance) [SNOMED CT concept]
- olmesartan [MeSH concept]
- olmesartan [MeSH Supplementary Concept]
See also inter- (CISMeF)
- Product containing olmesartan (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Olmesartan (substance) [SNOMED CT concept]
- Product containing olmesartan (medicinal product) [SNOMED CT concept]
- olmesartan [MeSH concept]
- olmesartan [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
has_salt_form
- Olmesartan Medoxomil [NCIt concept]
is_free_acid_or_base_form_of
- Olmesartan Medoxomil [NCIt concept]

Keyword's position in hierarchy(ies) :

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