NCIt definition : A synthetic imidazole derivative and angiotensin II receptor antagonist with antihypertensive
activity. Olmesartan selectively binds to the angiotensin type 1 (AT1) receptor subtype
in vascular smooth muscle and adrenal gland, thereby competing with angiotensin II
for binding to the AT1 receptor. This prevents angiotensin II-induced vasoconstriction
and interferes with angiotensin II-mediated aldosterone secretion, thereby decreasing
aldosterone production and preventing aldosterone-stimulated sodium retention and
potassium excretion.;
UNII : 8W1IQP3U10;
InChIKey : VTRAEEWXHOVJFV-UHFFFAOYSA-N;
CAS number : 144689-24-7; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 144689-24-7
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