" /> Olmesartan Medoxomil - CISMeF





Preferred Label : Olmesartan Medoxomil;

NCIt synonyms : 1H-Imidazole-5-carboxylic Acid, 4-(1-hydroxy-1-methylethyl)-2-propyl-1-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-,(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl Ester;

NCIt definition : A synthetic imidazole derivative prodrug with an antihypertensive property. Upon hydrolysis, olmesartan medoxomil is converted to olmesartan. Olmesartan selectively binds to the angiotensin type 1 (AT1) receptor of angiotensin II in vascular smooth muscle and adrenal gland, thereby competing angiotensin II binding to the receptor. This prevents angiotensin II-induced vasoconstriction and decreases aldosterone production, thereby preventing aldosterone-stimulated sodium retention and potassium excretion.;

UNII : 6M97XTV3HD;

InChIKey : UQGKUQLKSCSZGY-UHFFFAOYSA-N;

CAS number : 144689-63-4; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 144689-63-4 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Benicar;

Molecule name : CS 866;

Chemical formula : C29H30N6O6;

Codes from synonyms : 32062;

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22/05/2024


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