" /> Mometasone - CISMeF





Preferred Label : Mometasone;

NCIt definition : A synthetic topical glucocorticoid receptor (GR) agonist with anti-inflammatory, anti-pruritic and vasoconstrictive properties. Upon administration, mometasone binds to cytoplasmic GRs and subsequently activates GR-mediated gene expression. This results in the synthesis of certain anti-inflammatory proteins, while inhibiting the synthesis of certain inflammatory mediators. Specifically, mometasone appears to induce phospholipase A2 inhibitory proteins, thereby controlling the release of the inflammatory precursor arachidonic acid from phospholipid membrane by phospholipase A2.;

Alternative definition : NCI-GLOSS: A drug that is used in a cream to treat certain skin conditions and in a nasal spray to treat sinus problems caused by allergies. It is being studied as a way to treat inflammation of the skin caused by radiation therapy. Mometasone is a type of corticosteroid.;

UNII : 8HR4QJ6DW8;

InChIKey : QLIIKPVHVRXHRI-CXSFZGCWSA-N;

CAS number : 105102-22-5; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 105102-22-5 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Chemical formula : C22H28Cl2O4;

ChEBI ID : CHEBI:6970;

Codes from synonyms : CDR0000572207;

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21/05/2024


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