NCIt definition : A quinazoline derivative with antineoplastic properties. Competing with adenosine
triphosphate, erlotinib reversibly binds to the intracellular catalytic domain of
epidermal growth factor receptor (EGFR) tyrosine kinase, thereby reversibly inhibiting
EGFR phosphorylation and blocking the signal transduction events and tumorigenic effects
associated with EGFR activation.;
UNII : J4T82NDH7E;
InChIKey : AAKJLRGGTJKAMG-UHFFFAOYSA-N;
CAS number : 183321-74-6; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 183321-74-6
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